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Ubiquitin E3 ligases

This repository contains data and code utilized for the metric-learning based classification of the “human E3 ligome”–an extensive set of catalytic human E3s–by integrating multi-layered data, including protein sequences, domain architectures, 3D structures, functions, and expression pattern. Manuscript: https://www.biorxiv.org/content/10.1101/2025.03.09.642240v1.full.pdf