DPCfam

Project information

This repository contiains the implementation of DPC-based algorithm as described in Russo, E.T., Laio, A. & Punta, M. Density Peak clustering of protein sequences associated to a Pfam clan reveals clear similarities and interesting differences with respect to manual family annotation. BMC Bioinformatics 22, 121 (2021). https://doi.org/10.1186/s12859-021-04013-x. Note that the implementation has been written with the puropose of analysing, on a traditional workstation (8GB ram, 4-8 cores), query datasets with up to 5000 proteins, as those analysed in the reference paper.

clustering